Web Summary
Q1: What is the address of Premas Biotech's headquarters?
A1: The address of Premas Biotech's headquarters in the United States is 13 High Field Lane, Madison, CT 06443. Additionally, they have offices in India located at Plot 77, Sector 4, IMT Manesar, Gurugram 122050, and Plot 79B80B, Sector 5, IMT Manesar.
Q2: What is the primary focus of Premas Biotech's services?
A2: The primary focus of Premas Biotech's services is to provide integrated solutions for protein expression, purification, and formulation. They offer a range of services including scouting, cell line development, process development, scaleup and manufacturing, analytical development, and functional assays.
Q3: What is the purpose of Premas Biotech's Axtex4D technology?
A3: The Axtex4D technology is a proprietary platform developed by Premas Biotech to optimize protein expression. It allows for rapid screening of 2000+ data points across four host expression systems (bacteria, yeast, and mammalian cells) to identify key parameters that enhance protein expression.
Q4: What types of proteins are challenging to express and purify?
A4: Difficulttoexpress proteins, such as membraneassociated proteins with high numbers of cysteine residues and proline residues, pose significant challenges in producing soluble expression and subsequent purification. These proteins are also susceptible to degradation and aggregation, making protein stability screening crucial.
Q5: What is the purpose of Premas Biotech's 48well plate formulation study?
A5: The 48well plate formulation study is a method developed by Premas Biotech to optimize protein formulations, including buffers, additives, stabilizers, excipients, etc. This study aims to stabilize proteins against physicochemical degradation and aggregation over the desired shelf life.
Q6: What are some of the key factors that influence protein stability?
A6: Factors such as temperature, pH, buffer composition, salt, metalions, cosolvents, preservatives, surfactants, protein concentration, and freezethaw cycles significantly impact protein stability in a solution.
Q7: What is Premas Biotech's approach to delivering proteins for various applications?
A7: Premas Biotech has developed a range of technologies and services to deliver proteins for various applications, including vaccine development, therapeutics, and other industries. They offer rapid expression optimization platforms, purification screens, formulation studies, and analytical development and functional assays.
Q8: How can customers contact Premas Biotech?
A8: Customers can contact Premas Biotech through their website or by reaching out to them directly via phone, email, or inperson at one of their offices. They also offer a collaboration opportunity for interested parties to discuss potential projects or partnerships.